منابع مشابه
[Role of genomic medicine in middle and inner ear diseases].
INTRODUCTION AND OBJECTIVES Genomic medicine investigates groups of genetic markers that determine susceptibility for complex diseases. The aim of this review was to introduce genomics to the clinical otorhinolaryngologist. Technological advances in genotyping and sequencing that have facilitated genome-wide association studies in common causes of hearing loss during the last years are summaris...
متن کاملZebrafish models of human eye and inner ear diseases.
Eye and inner ear diseases are the most common sensory impairments that greatly impact quality of life. Zebrafish have been intensively employed to understand the fundamental mechanisms underlying eye and inner ear development. The zebrafish visual and vestibulo-acoustic systems are very similar to these in humans, and although not yet mature, they are functional by 5days post-fertilization (dp...
متن کاملAutoimmune Inner Ear Disease- A Clinical Viewpoint
Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic to...
متن کاملProteomics and the Inner Ear
The inner ear, one of the most complex organs, contains within its bony shell three sensory systems, the evolutionary oldest gravity receptor system, the three semicircular canals for the detection of angular acceleration, and the auditory system--unrivaled in sensitivity and frequency discrimination. All three systems are susceptible to a host of afflictions affecting the quality of life for a...
متن کاملInside the inner ear
There are dozens of different myosin isozymes, though it's not clear why cells require such a diversity. These images of fluorescently-labelled hair cells from the inner ears of frog, guinea pig and mouse show the localization of actin (red at top left and bottom right) and of four different forms of myosin (green, except at bottom left, where myosin VI is labelled in red). Hair cells are the r...
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ژورنال
عنوان ژورنال: Practica Oto-Rhino-Laryngologica
سال: 2001
ISSN: 1884-4545,0032-6313
DOI: 10.5631/jibirin.94.957